Region 1
Clinched Playoff Berth: Lisbon
- Hatton/Northwood (3-2 region, 4-3 overall) at Lisbon (5-0 region, 6-0 overall)
- Lisbon clinches region title with a win
- Hatton/Northwood clinches a playoff berth with a win AND a Northern Cass loss
- Oakes (4-1 region, 5-1 overall) and Thompson (3-2 region, 4-2 overall)
- Both team clinch playoff berths with a win
Region 2
Clinched Playoff Berth: Langdon/Edmore/Munich
- Langdon/Edmore/Munich (5-0 region, 7-0 overall)
- Clinches region title with a win OR if Grafton and Harvey/Wells County both lose
- Harvey/Wells County (4-1 region, 4-3 overall)
- Clinches playoff berth and the #2 seed with a win
- Also clinches a playoff berth with either a Rugby or Grafton loss
- Rugby (3-2 region, 5-2 overall) and Grafton (3-2 region, 5-2 overall)
- Both teams clinch playoff berths with a win
Region 3
Clinched Playoff Berth: Des Lacs-Burlington and Velva
- Velva (5-0 region, 6-0 overall)
- Clinches region title with a win
- Des Lacs-Burlington (4-1 region, 5-2 overall) at Bishop Ryan (4-1 region, 6-1 overall)
- Winner clinches at least the #2 seed
- Bishop Ryan clinches a playoff berth with a win OR either Garrison/Max or Kenmare/Bowbells/BC lose
- Kenmare/Bowbells/BC (3-2 region, 4-2 overall)
- Clinches playoff berth with a win OR a Garrison/Max loss
Region 4
Clinched Playoff Berth: Bowman County, New Salem/Glen Ullin, and Shiloh Christian
- Bowman County (5-0 region, 5-1 overall)
- Clinches at least the #2 seed with a win
- Clinches region title with a win AND a New Salem/Glen Ullin loss
- Shiloh Christian (4-1 region, 6-1 overall)
- Clinches the #2 seed with a win AND losses by both Dickinson Trinity and New Salem/Glen Ullin
- Clinches at least the #3 seed with a win AND a Dickinson Trinity loss
- New Salem/Glen Ullin (4-1 region, 6-1 overall)
- Clinches at least the #3 seed with a win OR Dickinson Trinity loss
- Dickinson Trinity (3-2 region, 3-3 overall)
- Clinches playoff berth with a win