NOTE: Forfeits against Garrison/Max in Region 4 are excluded from each teams record.
Region 1
- Hillsboro/Central Valley (4-0) @ Kindred (4-0)
- Winner clinches playoff berth (and a chance to clinch the region title next week)
- Loser clinches playoff berth with a Milnor/North Sargent loss
Region 2
- Langdon/Edmore/Munich (4-0) @ Carrington (4-0)
- Winner clinches playoff berth (and a chance to clinch the region title next week)
- Loser clinches playoff berth if both Harvey/Wells County AND Rugby lose
Region 3
- New Town (0-4) @ Bishop Ryan (4-0)
- Bishop Ryan clinches a playoff berth with either:
- A win
OR - A Nedrose loss
OR - A Lewis & Clark/Our Redeemers loss
- A win
- Bishop Ryan clinches a playoff berth with either:
- Nedrose (2-2) @ Velva (4-0)
- Velva clinches a playoff berth with either:
- A win
OR - A Des Lacs-Burlington loss
- A win
- Velva clinches a playoff berth with either:
Region 4
- Bowman County (4-0) @ Hazen (2-1)
- Bowman County clinches a playoff berth with a win OR a Killdeer loss
- Bowman County can clinch the Region 4 title with:
- A win
AND - A Dickinson Trinity loss
AND - A Beulah loss
- A win
- Killdeer (1-2) @ Dickinson Trinity (3-1)
- Dickinson Trinity clinches a playoff berth with a win